Nucleo Longevity

Magnesium

magnesium · magnesium glycinate · magnesium citrate · magnesium threonate

An essential mineral widely supplemented for sleep, muscle, mood and heart health.

TipoSupplement / dietary

Il voto risponde a: What does the human evidence support for: Deficiency correction, sleep & metabolic support?

Grado

C

Limitata

Il voto misura la qualità dell'evidenza, non è un consiglio ad assumere o acquistare.

Classe
Essential mineral
Uso principale
Deficiency correction, sleep & metabolic support
Forza evidenza
medium
Ultima revisione
2026-07-01

In sintesi

Correcting a real shortfall is worthwhile and many people under-consume it — but magnesium is not a longevity intervention, and 'more' past sufficiency doesn't help. Fix a deficiency, don't chase a miracle.

Cosa dice l'evidenza

Magnesium is genuinely essential for hundreds of enzymatic reactions, and a meaningful share of people don't hit recommended intakes. Supplementation has modest, reasonably supported benefits for sleep quality, blood pressure and possibly muscle cramps, particularly in those who are low. What it is not is a proven longevity or disease-prevention pill for the already-sufficient. Grade C: real value in correcting a shortfall, oversold as a cure-all.

Studi chiave

  1. [1]

    Magnesium supplementation and blood pressure · meta-analysis

    Small reductions, larger in deficient/hypertensive people.

    Apri su PubMed
  2. [2]

    Magnesium and sleep quality · review

    Modest, inconsistent benefit; better evidence in the deficient.

    Apri su PubMed
  3. [3]

    Magnesium status and health outcomes (review) · review

    Deficiency matters; supraphysiologic dosing does not add benefit.

    Apri su PubMed
Vedi tutti gli studi su PubMed

Meccanismo

A cofactor in ATP metabolism, DNA/protein synthesis, nerve and muscle function, and vascular tone; low status disrupts many of these processes.

Sicurezza

Safe from food and at typical supplement doses. Excess supplemental magnesium (especially oxide) commonly causes diarrhoea; very high intake is risky in kidney impairment. Different salts differ mainly in absorption and laxative effect, not magic.

Contesto dosaggio

Typical supplemental doses are ~200–400 mg elemental magnesium/day. Glycinate/citrate are better tolerated than oxide; 'threonate' is marketed for the brain on limited human data.

Esempi di applicazione

  • Taken as glycinate/citrate (~200–400 mg elemental), often in the evening.
  • Aimed at correcting a real shortfall, not mega-dosing.
  • Oxide is cheap but poorly absorbed and more laxative.

Nota dal campo

Magnesium is a case where the boring advice is the right advice: many people are genuinely low, correcting that helps a bit, and beyond sufficiency there's nothing to chase. C, not a longevity headline.

Dove acquistare

demo

Confronto di prezzo e reperibilità presso venditori che operano in Italia. Il prezzo mostrato è indicativo: verifica sempre sul sito del venditore.

VenditorePrezzoSpedizioneTotalePrezzo unitarioAggiornato
Demo Store B
Magnesium glycinate — 120 caps (demo)
€15.90da verificaren/d€0.13 /cap2026-07-07Vai al negozio
Demo Store A
Magnesium glycinate — 90 caps (demo)
€12.90€3.90€16.80€0.14 /cap2026-07-10Vai al negozio

Dati dimostrativi — offerte fittizie a scopo illustrativo, non prezzi reali. Núkleo non ha accordi commerciali con questi venditori: i link sono link esterni normali. Il confronto non include necessariamente tutti i venditori sul mercato. Come funziona il confronto.