Nucleo Longevity
ENIT

Analysis

Analysis

Deep-dives based on peer-reviewed studies.

C

Berberine · Metabolism

Berberine, the alleged "natural Ozempic": what the studies say

Berberine has real metabolic effects — and a false commercial comparison. What the RCTs show, and why the interaction risk matters more than you're told.

2026-08-18

3 min read

B

Ceramides · Skin longevity

Ceramides and the skin barrier: ingredient evidence versus product claims

The clearest case of the gap between 'the ingredient has evidence' and 'this product works'. Why the lipid ratio matters more than the word on the label.

2026-08-18

3 min read

B

Creatine · Performance and muscle mass

Creatine and aging: what human studies actually show

Creatine is cheap, unglamorous and better evidenced than most 'longevity' molecules. What it actually proves in older adults, and what it doesn't.

2026-08-18

3 min read

A

Sunscreen (SPF) · Skin longevity

Photoprotection is a longevity intervention (not skincare)

In a category full of hyped serums, the winner is boring: daily sunscreen is the only topical we grade A. Here's why.

2026-08-18

3 min read

B

NMN / NR · Cellular metabolism

NR vs NMN: which NAD+ precursor actually makes sense

NMN and NR are sold as rivals. In human data they are near-identical: both raise NAD⁺, neither has shown clinical benefit. What actually differs between them.

2026-08-18

4 min read

C

Vitamin D · Micronutrients

Vitamin D: who actually benefits (and who takes it pointlessly)

Vitamin D is unusual: both the enthusiasm and the disappointment are evidence-based. The value is concentrated in the deficient — and nearly absent in everyone else.

2026-08-18

3 min read

B

NMN · Cellular metabolism

NMN: What clinical studies really say in 2024

A critical review of human NMN studies: what is proven, what is still hypothetical, and why grade B is justified.

2026-06-15

4 min read