Nucleo Longevity

Quercetin

quercetin

A flavonoid with senolytic action, often combined with dasatinib.

Grade

C

Limited

Class
Senolytics
Primary use
Senolytic action
Evidence strength
low
Last reviewed
2025-09-01

The claim

A flavonoid with senolytic action, often combined with dasatinib.

What the evidence says

Interesting preclinical senolytic data; in humans the data are early and the protocols (D+Q) experimental.

Key studies

  1. [1]

    Quercetin / senolytics in humans (PubMed) · review

    Human evidence still preliminary.

    PubMed

Mechanism

Selective induction of apoptosis in senescent cells; antioxidant and anti-inflammatory activity.

Safety

Good tolerability as a dietary component; senolytic protocols belong in a clinical setting.

Dosage context

Low bioavailability; doses and cycles vary widely across studies.

From the field

The senolytic field is promising but young: caution on the grade.

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